MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol

<p>Abstract</p> <p>Background</p> <p>Substantial data indicate that the oncogene microRNA 21 (miR-21) is significantly elevated in glioblastoma multiforme (GBM) and regulates multiple genes associated with cancer cell proliferation, apoptosis, and invasiveness. Thus, mi...

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Bibliographic Details
Main Authors: Wang Guang-Xiu, Han Lei, Yuan Xu-Bo, Mei Mei, Zhou Xuan, Ren Yu, Jia Zhi-Fan, Xu Peng, Pu Pei-Yu, Kang Chun-Sheng
Format: Article
Language:English
Published: BMC 2010-01-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/27