Dihydroartemisinin imposes positive and negative regulation on Treg and plasma cells via direct interaction and activation of c-Fos

Dihydroartemisinin (DHA) promotes Treg cell proliferation and suppresses plasma cell expansion through direct interaction and activation of c-Fos, underling the bilateral immunoregulatory mechanism of DHA.

Bibliographic Details
Main Authors: Qilong Li, Ning Jiang, Yiwei Zhang, Yize Liu, Ziwei Su, Quan Yuan, Xiaoyu Sang, Ran Chen, Ying Feng, Qijun Chen
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04454-5