Activation of the Nrf2 Pathway as a Therapeutic Strategy for ALS Treatment
Amyotrophic lateral sclerosis is a progressive and fatal disease that causes motoneurons degeneration and functional impairment of voluntary muscles, with limited and poorly efficient therapies. Alterations in the Nrf2-ARE pathway are associated with ALS pathology and result in aberrant oxidative st...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-02-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/27/5/1471 |