Regulation of platelet numbers and sizes by signaling pathways

Regulation of platelet numbers and sizes by signaling pathways

Either the glycoprotein (GP) Ib deficiency or hyper-function in humans can cause macrothrombocytopenia, the molecular mechanisms of which remain unclear. Herein, the investigations for disease pathogenesis were performed in the human induced pluripotent stem cell (hiPSC) model. The hiPSCs carrying a...

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Bibliographic Details
Main Authors: Jaturawat Pawinwongchai, Ponthip Mekchay, Nungruthai Nilsri, Nipan Israsena, Ponlapat Rojnuckarin
Format: Article
Language:English
Published: Taylor & Francis Group 2021-11-01
Series:Platelets
Subjects:
platelet-type von willebrand disease
bernard–soulier syndrome
human-induced pluripotent stem cell (ipsc)
macrothrombocytopenia
proplatelet formation
mitogen-activated protein kinase
Online Access:http://dx.doi.org/10.1080/09537104.2020.1841893

Internet

http://dx.doi.org/10.1080/09537104.2020.1841893

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