Spirolactone provides protection from renal fibrosis by inhibiting the endothelial–mesenchymal transition in isoprenaline-induced heart failure in rats

Spirolactone provides protection from renal fibrosis by inhibiting the endothelial–mesenchymal transition in isoprenaline-induced heart failure in rats

Hao Zhou, Dan Xi, Jichen Liu, Jinjin Zhao, Si Chen, Zhigang Guo Division of Cardiology, Huiqiao Medical Center, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, People’s Republic of China Background: Fibrosis results in excessive accumulation of extracellular matrix p...

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Bibliographic Details
Main Authors: Zhou H, Xi D, Liu J, Zhao J, Chen S, Guo Z
Format: Article
Language:English
Published: Dove Medical Press 2016-05-01
Series:Drug Design, Development and Therapy
Subjects:
spironolactone
heart failure
renal fibrosis
transforming growth factor
endothelial-mesenchymal transition
Online Access:https://www.dovepress.com/spirolactone-provides-protection-from-renal-fibrosis-by-inhibiting-the-peer-reviewed-article-DDDT

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https://www.dovepress.com/spirolactone-provides-protection-from-renal-fibrosis-by-inhibiting-the-peer-reviewed-article-DDDT

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