Application of the target trial emulation framework to external comparator studies

External comparator (EC) studies are increasingly being used to generate evidence that supports the evaluation of emerging pharmacological treatments for regulatory and health technology assessment (HTA) purposes. However, the reliability of evidence generated from EC studies can vary. In this paper...

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Bibliographic Details
Main Authors: Kellyn Arnold, Luis Antunes, Briana Coles, Hopin Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Drug Safety and Regulation
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fdsfr.2024.1380568/full