Synthetic antioxidant TS-13 reduces doxorubicin cardiotoxicity

Synthetic antioxidant TS-13 reduces doxorubicin cardiotoxicity

The antitumor antibiotic doxorubicin, a representative of a large group of anthriacyclines, is widely and quite effectively used to treat patients with malignant neoplasms. The aim of this study was to study the effect of TS-13, a synthetic phenolic antioxidant and an activator of the antioxidant-re...

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Bibliographic Details
Main Authors: E. B. Menshchikova, R. A. Knyazev, N. V. Trifonova, N. A. Deeva, A. R. Kolpakov, L. P. Lidia P. Romakh, N. V. Kandalintseva
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Siberian Branch Publishing House 2023-10-01
Series:Сибирский научный медицинский журнал
Subjects:
doxorubicin
isolated heart
rats
cardiotoxicity
oxidative stress
antioxidants
keap1/nrf2/are signaling system
Online Access:https://sibmed.elpub.ru/jour/article/view/1248

Internet

https://sibmed.elpub.ru/jour/article/view/1248

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