Antiproliferative and apoptotic activity of gemcitabine-lauric acid conjugate on human bladder cancer cells
Objective(s): Gemcitabine is a first-line drug for the treatment of bladder cancer. One of the most important mechanisms of gemcitabine resistance is the low expression of cellular membrane transporter hENT1. Various derivatives containing fatty acid side chains have been developed in order to facil...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Mashhad University of Medical Sciences
2022-04-01
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Series: | Iranian Journal of Basic Medical Sciences |
Subjects: | |
Online Access: | https://ijbms.mums.ac.ir/article_20088_e423ed5179cc59bbfc8f69a34672a776.pdf |