Split selectable markers

Selectable markers are widely used in cell engineering but there is only a limited variety to choose from. Here the authors split markers using inteins, allowing up to six transgene integration events to be selected for with one marker.

Dades bibliogràfiques
Autors principals: Nathaniel Jillette, Menghan Du, Jacqueline Jufen Zhu, Peter Cardoz, Albert Wu Cheng
Format: Article
Idioma:English
Publicat: Nature Portfolio 2019-10-01
Col·lecció:Nature Communications
Accés en línia:https://doi.org/10.1038/s41467-019-12891-2
Descripció
Sumari:Selectable markers are widely used in cell engineering but there is only a limited variety to choose from. Here the authors split markers using inteins, allowing up to six transgene integration events to be selected for with one marker.
ISSN:2041-1723