Synthesis and Biological Evaluation of 6-<i>O</i>-Sucrose Monoester Glycolipids as Possible New Antifungal Agents

Synthesis and Biological Evaluation of 6-<i>O</i>-Sucrose Monoester Glycolipids as Possible New Antifungal Agents

A small library of 6-<i>O</i>-sucrose monoester surfactants has been synthesized and tested against various microorganisms. The synthetic procedure involved a modified Mitsunobu reaction, which showed improved results compared to those present in the literature (higher yields and larger...

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Bibliographic Details
Main Authors: Michele Verboni, Maurizio Sisti, Raffaella Campana, Serena Benedetti, Francesco Palma, Lucia Potenza, Simone Lucarini, Andrea Duranti
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pharmaceuticals
Subjects:
glycolipids
sucrose monoesters
sugar-based surfactants
minimum inhibitory concentration (MIC)
antifungal activity
anti-inflammatory activity
Online Access:https://www.mdpi.com/1424-8247/16/2/136

Internet

https://www.mdpi.com/1424-8247/16/2/136

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