RHAMM deficiency disrupts folliculogenesis resulting in female hypofertility
The postnatal mammalian ovary contains the primary follicles, each comprising an immature oocyte surrounded by a layer of somatic granulosa cells. Oocytes reach meiotic and developmental competence via folliculogenesis. During this process, the granulosa cells proliferate massively around the oocyte...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2015-03-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/4/4/562 |