Lipid hydroperoxides promote sarcopenia through carbonyl stress

Lipid hydroperoxides promote sarcopenia through carbonyl stress

Reactive oxygen species (ROS) accumulation is a cardinal feature of skeletal muscle atrophy. ROS refers to a collection of radical molecules whose cellular signals are vast, and it is unclear which downstream consequences of ROS are responsible for the loss of muscle mass and strength. Here, we show...

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Bibliographic Details
Main Authors: Hiroaki Eshima, Justin L Shahtout, Piyarat Siripoksup, MacKenzie J Pearson, Ziad S Mahmassani, Patrick J Ferrara, Alexis W Lyons, John Alan Maschek, Alek D Peterlin, Anthony RP Verkerke, Jordan M Johnson, Anahy Salcedo, Jonathan J Petrocelli, Edwin R Miranda, Ethan J Anderson, Sihem Boudina, Qitao Ran, James E Cox, Micah J Drummond, Katsuhiko Funai
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-03-01
Series:eLife
Subjects:
skeletal muscle
lipid peroxidation
oxidative stress
sarcopenia
muscle atrophy
Online Access:https://elifesciences.org/articles/85289

Internet

https://elifesciences.org/articles/85289

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