Luteolin Isolated from the Flowers of Lonicera japonica Suppresses Inflammatory Mediator Release by Blocking NF-κB and MAPKs Activation Pathways in HMC-1 Cells

Luteolin Isolated from the Flowers of Lonicera japonica Suppresses Inflammatory Mediator Release by Blocking NF-κB and MAPKs Activation Pathways in HMC-1 Cells

Luteolin (3′,4′,5,7-tetrahydroxylflavone) is a plant flavonoid and pharmacologically active agent that has been isolated from several plant species. In the present study, the effect of luteolin from the flowers of Lonicera japonica on phorbol 12-myristate 13-acetate (PMA) plus A23187-induced mast ce...

Full description

Bibliographic Details
Main Authors: John-Hwa Lee, Dong-Yeul Kwon, Jang-Gi Choi, Ok-Hwa Kang
Format: Article
Language:English
Published: MDPI AG 2010-01-01
Series:Molecules
Subjects:
Lonicera japonica
pro-inflammatory cytokine
intracellular Ca2+
NF-κB
MAPKs
Online Access:http://www.mdpi.com/1420-3049/15/1/385/

Internet

http://www.mdpi.com/1420-3049/15/1/385/

Similar Items