C-X-C Motif Chemokine Ligand 9 and Its CXCR3 Receptor Are the Salt and Pepper for T Cells Trafficking in a Mouse Model of Gaucher Disease

C-X-C Motif Chemokine Ligand 9 and Its CXCR3 Receptor Are the Salt and Pepper for T Cells Trafficking in a Mouse Model of Gaucher Disease

Gaucher disease is a lysosomal storage disease, which happens due to mutations in <i>GBA1</i>/<i>Gba1</i> that encodes the enzyme termed as lysosomal acid β-glucosidase. The major function of this enzyme is to catalyze glucosylceramide (GC) into glucose and ceramide. The defi...

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Bibliographic Details
Main Authors: Albert Frank Magnusen, Reena Rani, Mary Ashley McKay, Shelby Loraine Hatton, Tsitsi Carol Nyamajenjere, Daniel Nii Aryee Magnusen, Jörg Köhl, Gregory Alex Grabowski, Manoj Kumar Pandey
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
lysosomal storage disease
chemokine
chemokine receptor
inflammation
Online Access:https://www.mdpi.com/1422-0067/22/23/12712

Internet

https://www.mdpi.com/1422-0067/22/23/12712

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