Macrophage membrane-mediated targeted drug delivery for treatment of spinal cord injury regardless of the macrophage polarization states

Macrophage membrane-mediated targeted drug delivery for treatment of spinal cord injury regardless of the macrophage polarization states

Targeted delivery of therapeutics for spinal cord injury (SCI) has been a long-term challenge due to the complexity of the pathological procession. Macrophage, as an immune cell, can selectively accumulate at the trauma site after SCI. This intrinsic targeting, coupled with good immune-escaping capa...

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Bibliographic Details
Main Authors: Wei Tang, Yi Yang, Ling Yang, Mei Tang, Ying Chen, Chong Li
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Spinal cord injury
Pyroptosis
Macrophage polarization
Minocycline
Actively targeted delivery
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087621000350

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http://www.sciencedirect.com/science/article/pii/S1818087621000350

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