Mild thermotherapy and hyperbaric oxygen enhance sensitivity of TMZ/PSi nanoparticles via decreasing the stemness in glioma

Mild thermotherapy and hyperbaric oxygen enhance sensitivity of TMZ/PSi nanoparticles via decreasing the stemness in glioma

Abstract Background Glioma is a common brain tumor with a high mortality rate. A small population of cells expressing stem-like cell markers in glioma contributes to drug resistance and tumor recurrence. Methods Porous silicon nanoparticles (PSi NPs) as photothermal therapy (PTT) agents loaded with...

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Bibliographic Details
Main Authors: Xiaofan Zeng, Qi Wang, Xuan Tan, Le Jia, Yuwei Li, Mingdi Hu, Zhijie Zhang, Xicheng Bai, Yanhong Zhu, Xiangliang Yang
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Journal of Nanobiotechnology
Subjects:
Glioma
Photothermal therapy
Hyperbaric oxygen
Porous silicon nanoparticles
Stemness
Online Access:http://link.springer.com/article/10.1186/s12951-019-0483-1

Internet

http://link.springer.com/article/10.1186/s12951-019-0483-1

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