COPPER-UPTAKE IS CRITICAL FOR THE DOWN REGULATION OF SYNAPSIN AND DYNAMIN INDUCED BY NEOCUPROINE: MODULATION OF SYNAPTIC ACTIVITY IN HIPPOCAMPAL NEURONS

COPPER-UPTAKE IS CRITICAL FOR THE DOWN REGULATION OF SYNAPSIN AND DYNAMIN INDUCED BY NEOCUPROINE: MODULATION OF SYNAPTIC ACTIVITY IN HIPPOCAMPAL NEURONS

Extracellular and intracellular copper and zinc regulate synaptic activity and synaptic plasticity, which may impact brain functionality and human behavior. We have found that a metal coordinating molecule, Neocuproine, transiently increases free intracellular copper and zinc levels (i.e. min) in hi...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính: Patricio A Castro, Alejandra eRamirez, Fernando J Sepulveda, Christian ePeters, Humberto eFierro, Javier eWaldron, Sandra eLuza, Jorge eFuentealba, Jose F Munoz, Giancarlo V De Ferrari, Ashley Ian Bush, Luis G Aguayo, Carlos M Opazo
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: Frontiers Media S.A. 2014-12-01
Loạt:Frontiers in Aging Neuroscience
Những chủ đề:
Copper
Zinc
hyperexcitability
Synapsin
dynamin
neocuproine
Truy cập trực tuyến:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00319/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00319/full

Những quyển sách tương tự