COPPER-UPTAKE IS CRITICAL FOR THE DOWN REGULATION OF SYNAPSIN AND DYNAMIN INDUCED BY NEOCUPROINE: MODULATION OF SYNAPTIC ACTIVITY IN HIPPOCAMPAL NEURONS

COPPER-UPTAKE IS CRITICAL FOR THE DOWN REGULATION OF SYNAPSIN AND DYNAMIN INDUCED BY NEOCUPROINE: MODULATION OF SYNAPTIC ACTIVITY IN HIPPOCAMPAL NEURONS

Extracellular and intracellular copper and zinc regulate synaptic activity and synaptic plasticity, which may impact brain functionality and human behavior. We have found that a metal coordinating molecule, Neocuproine, transiently increases free intracellular copper and zinc levels (i.e. min) in hi...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Patricio A Castro, Alejandra eRamirez, Fernando J Sepulveda, Christian ePeters, Humberto eFierro, Javier eWaldron, Sandra eLuza, Jorge eFuentealba, Jose F Munoz, Giancarlo V De Ferrari, Ashley Ian Bush, Luis G Aguayo, Carlos M Opazo
स्वरूप: लेख
भाषा:English
प्रकाशित: Frontiers Media S.A. 2014-12-01
श्रृंखला:Frontiers in Aging Neuroscience
विषय:
Copper
Zinc
hyperexcitability
Synapsin
dynamin
neocuproine
ऑनलाइन पहुंच:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00319/full

इंटरनेट

http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00319/full

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