Short-Term Effects of Elexacaftor/Tezacaftor/Ivacaftor Combination on Glucose Tolerance in Young People With Cystic Fibrosis—An Observational Pilot Study

Short-Term Effects of Elexacaftor/Tezacaftor/Ivacaftor Combination on Glucose Tolerance in Young People With Cystic Fibrosis—An Observational Pilot Study

BackgroundThe effect of elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) on glucose tolerance and/or cystic-fibrosis-related diabetes (CFRD) is not well understood. We performed an observational study on the short-term effects of ELX/TEZ/IVA on glucose tolerance.MethodsSixteen adolescents with CF perf...

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Bibliographic Details
Main Authors: Insa Korten, Elisabeth Kieninger, Linn Krueger, Marina Bullo, Christa E. Flück, Philipp Latzin, Carmen Casaulta, Claudia Boettcher
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Pediatrics
Subjects:
cystic fibrosis
elexacaftor/tezacaftor/ivacaftor therapy
oral glucose tolerance test (OGTT)
continuous glucose monitoring
glucose tolerance
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2022.852551/full

Internet

https://www.frontiersin.org/articles/10.3389/fped.2022.852551/full

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