B Cells and Progressive Multifocal Leukoencephalopathy: Search for the Missing Link

B Cells and Progressive Multifocal Leukoencephalopathy: Search for the Missing Link

Progressive multifocal leukoencephalopathy (PML) is a deadly demyelinating disease due to JC virus (JCV) replication in the brain. PML classically occurs in patients with severe immunodepression, and cases have recently been linked to therapeutic monoclonal antibodies such as natalizumab and also ri...

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Bibliographic Details
Main Authors: Deniz eDurali, Marie-Ghislaine ede Goër de Herve, Jacques eGasnault, Yassine eTaoufik
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Immunology
Subjects:
JC Virus
T cells
B cells
Immune Regulation
progressive multifocal leukoencephalopathy
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00241/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00241/full

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