On the evolutionary ecology of multidrug resistance in bacteria.

Resistance against different antibiotics appears on the same bacterial strains more often than expected by chance, leading to high frequencies of multidrug resistance. There are multiple explanations for this observation, but these tend to be specific to subsets of antibiotics and/or bacterial speci...

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Bibliographic Details
Main Authors: Sonja Lehtinen, François Blanquart, Marc Lipsitch, Christophe Fraser, with the Maela Pneumococcal Collaboration
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007763