Interleukin-1α links peripheral CaV2.2 channel activation to rapid adaptive increases in heat sensitivity in skin

Abstract Neurons have the unique capacity to adapt output in response to changes in their environment. Within seconds, sensory nerve endings can become hypersensitive to stimuli in response to potentially damaging events. The underlying behavioral response is well studied, but several of the key sig...

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Bibliographic Details
Main Authors: Anne-Mary N. Salib, Meredith J. Crane, Sang Hun Lee, Brian J. Wainger, Amanda M. Jamieson, Diane Lipscombe
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-59424-6