Epigenetic Regulation of BST-2 Expression Levels and the Effect on HIV-1 Pathogenesis

Epigenetic Regulation of BST-2 Expression Levels and the Effect on HIV-1 Pathogenesis

HIV-1 must overcome host antiviral restriction factors for efficient replication. We hypothesized that elevated levels of bone marrow stromal cell antigen 2 (BST-2), a potent host restriction factor that interferes with HIV-1 particle release in some human cells and is antagonized by the viral prote...

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Bibliographic Details
Main Authors: Ravesh Singh, Veron Ramsuran, Vivek Naranbhai, Nonhlanhla Yende-Zuma, Nigel Garrett, Koleka Mlisana, Krista L. Dong, Bruce D. Walker, Salim S. Abdool Karim, Mary Carrington, Thumbi Ndung’u
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
BST-2
HIV-1
DNA methylation
epigenetic regulation
expression
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.669241/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.669241/full

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