Retro-enantio isomer of angiopep-2 assists nanoprobes across the blood-brain barrier for targeted magnetic resonance/fluorescence imaging of glioblastoma

Abstract Glioblastoma (GBM), one of the most common primary intracranial malignant tumours, is very difficult to be completely excised by surgery due to its irregular shape. Here, we use an MRI/NIR fluorescence dual-modal imaging nanoprobe that includes superparamagnetic iron oxide nanoparticles (SP...

Full description

Bibliographic Details
Main Authors: Ruoxi Xie, Zijun Wu, Fanxin Zeng, Huawei Cai, Dan Wang, Lei Gu, Hongyan Zhu, Su Lui, Gang Guo, Bin Song, Jinxing Li, Min Wu, Qiyong Gong
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00724-y