A dual-purpose humanized mouse model for testing antiviral strategies against both SIV and HIV

A dual-purpose humanized mouse model for testing antiviral strategies against both SIV and HIV

Nonhuman primate (NHP) models employing simian/simian-human immunodeficiency viruses (SIV/SHIVs) played a major role in the study of HIV pathogenesis, latency, and cure studies in a preclinical setting. However, it took many years to arrive at the current effective triple drug ARV regimen against SI...

Full description

Bibliographic Details
Main Authors: Ella Barnett, Snehal Kaginkar, Kimberly Schmitt, Leila Remling-Mulder, Ramesh Akkina
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Immunology
Subjects:
a dual-purpose hu-mouse model for HIV and SIV drug testing
anti-retroviral drug evaluation against SIV and HIV in humanized mice
a small animal model for SIV
emtricitabine/elvitegravir/tenofovir disoproxil fumarate (FTC/EVG/TDF) treatment for SIVmac239
emtricitabine/bictegravir/tenofovir alafenamide fumarate (FTC/BIC/TAF) treatment for SIVmac239
cART evaluations on SIV and HIV in humanized mice
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1491481/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1491481/full

Similar Items