Transforming growth factor-β in tumour development

Transforming growth factor-β in tumour development

Transforming growth factor-β (TGFβ) is a ubiquitous cytokine essential for embryonic development and postnatal tissue homeostasis. TGFβ signalling regulates several biological processes including cell growth, proliferation, apoptosis, immune function, and tissue repair following injury. Aberrant TGF...

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Bibliographic Details
Main Authors: Charles B. Trelford, Lina Dagnino, Gianni M. Di Guglielmo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Molecular Biosciences
Subjects:
transforming growth factor-b (TGFb)
Smad
receptor trafficking
epithelial-mesenchymal transition (EMT)
autophagy
protein 62/sequestosome 1 (p62/SQSTM1)
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.991612/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2022.991612/full

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