Brain Dopamine Transmission in Health and Parkinson's Disease: Modulation of Synaptic Transmission and Plasticity Through Volume Transmission and Dopamine Heteroreceptors

Brain Dopamine Transmission in Health and Parkinson's Disease: Modulation of Synaptic Transmission and Plasticity Through Volume Transmission and Dopamine Heteroreceptors

This perspective article provides observations supporting the view that nigro-striatal dopamine neurons and meso-limbic dopamine neurons mainly communicate through short distance volume transmission in the um range with dopamine diffusing into extrasynaptic and synaptic regions of glutamate and GABA...

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Bibliographic Details
Main Authors: Dasiel O. Borroto-Escuela, Miguel Perez De La Mora, Paul Manger, Manuel Narváez, Sarah Beggiato, Minerva Crespo-Ramírez, Gemma Navarro, Karolina Wydra, Zaida Díaz-Cabiale, Alicia Rivera, Luca Ferraro, Sergio Tanganelli, Małgorzata Filip, Rafael Franco, Kjell Fuxe
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
G protein-coupled receptor
dopamine receptor
heteroreceptor complexes
oligomerization
Parkinson's diseases
volume transmission
Online Access:https://www.frontiersin.org/article/10.3389/fnsyn.2018.00020/full

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https://www.frontiersin.org/article/10.3389/fnsyn.2018.00020/full

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