Tcf1 Sustains the Expression of Multiple Regulators in Promoting Early Natural Killer Cell Development

T cell factor 1 (Tcf1) is known as a critical mediator for natural killer (NK) cell development and terminal maturation. However, its essential targets and precise mechanisms involved in early NK progenitors (NKP) are not well clarified. To investigate the role of Tcf1 in NK cells at distinct develo...

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Main Authors: Juanjuan Liu, Zhao Wang, Shanshan Hao, Fang Wang, Yingpeng Yao, Yajiao Zhang, Yanyi Zhao, Wenhui Guo, Guotao Yu, Xiaohan Ma, Jingjing Liu, Feng Chen, Shunzong Yuan, Youmin Kang, Shuyang Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.791220/full