The voltage-gated sodium channel, para, limits Anopheles coluzzii vector competence in a microbiota dependent manner

Abstract The voltage-gated sodium channel, para, is a target of DDT and pyrethroid class insecticides. Single nucleotide mutations in para, called knockdown resistant or kdr, which contribute to resistance against DDT and pyrethroid insecticides, have been correlated with increased susceptibility of...

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Bibliographic Details
Main Authors: Luisa Nardini, Emma Brito-Fravallo, Pascal Campagne, Adrien Pain, Corinne Genève, Kenneth D. Vernick, Christian Mitri
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-40432-x