LncRNA GAS5 Overexpression Reverses LPS-Induced Inflammatory Injury and Apoptosis Through Up-Regulating KLF2 Expression in ATDC5 Chondrocytes

LncRNA GAS5 Overexpression Reverses LPS-Induced Inflammatory Injury and Apoptosis Through Up-Regulating KLF2 Expression in ATDC5 Chondrocytes

Background/Aims: Osteoarthritis (OA) is the most frequently occurring joint disease and characterized by degeneration of cartilage. As the unique cell type in cartilage, chondrocytes play a crucial role during OA. Our study explored the influence of long non-coding RNA (lncRNA) growth arrest-specifi...

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Bibliographic Details
Main Authors: Feng Li, Jianguang Sun, Shilei Huang, Gao Su, Guofu Pi
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
Osteoarthritis
LPS-induced injury
LncRNA GAS5
Kruppel-like factor 2
NF-κB and Notch pathways
Online Access:https://www.karger.com/Article/FullText/487455

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https://www.karger.com/Article/FullText/487455

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