<named-content content-type="genus-species">Staphylococcus aureus</named-content> Biofilms Induce Macrophage Dysfunction Through Leukocidin AB and Alpha-Toxin

<named-content content-type="genus-species">Staphylococcus aureus</named-content> Biofilms Induce Macrophage Dysfunction Through Leukocidin AB and Alpha-Toxin

ABSTRACT The macrophage response to planktonic Staphylococcus aureus involves the induction of proinflammatory microbicidal activity. However, S. aureus biofilms can interfere with these responses in part by polarizing macrophages toward an anti-inflammatory profibrotic phenotype. Here we demonstrat...

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Bibliographic Details
Main Authors: Tyler D. Scherr, Mark L. Hanke, Ouwen Huang, David B. A. James, Alexander R. Horswill, Kenneth W. Bayles, Paul D. Fey, Victor J. Torres, Tammy Kielian
Format: Article
Language:English
Published: American Society for Microbiology 2015-09-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01021-15

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https://journals.asm.org/doi/10.1128/mBio.01021-15

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