A revised road map for the commitment of human cord blood CD34-negative hematopoietic stem cells

A revised road map for the commitment of human cord blood CD34-negative hematopoietic stem cells

Single CD34 negative haematopoietic stem cells (HSCs) can fully reconstitute lympho-myeloid hematopoiesis in mice. Here, using single cell transplantation and gene expression analyses, the authors show that CD34 negative HSCs lie at the apex of haematopoiesis in human cord blood and that they can gi...

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Bibliographic Details
Main Authors: Keisuke Sumide, Yoshikazu Matsuoka, Hiroshi Kawamura, Ryusuke Nakatsuka, Tatsuya Fujioka, Hiroaki Asano, Yoshihiro Takihara, Yoshiaki Sonoda
Format: Article
Language:English
Published: Nature Portfolio 2018-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-04441-z

Internet

https://doi.org/10.1038/s41467-018-04441-z

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