Maternal protein malnutrition does not impair insulin secretion from pancreatic islets of offspring after transplantation into diabetic rats.

Pancreatic islets from adult rats whose mothers were protein restricted during lactation undersecrete insulin. The current work analyzes whether this secretory dysfunction can be improved when the pancreatic islets are grafted into hyperglycemic diabetic rats. Two groups of rats were used: the adult...

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Main Authors: Renato Chaves Souto Branco, Júlio Cezar de Oliveira, Sabrina Grassiolli, Rosiane Aparecida Miranda, Luiz Felipe Barella, Rodrigo Mello Gomes, Luiz Augusto Bataglini, Rosana Torrezan, Clarice Gravena, Paulo Cezar de Freitas Mathias
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22383969/pdf/?tool=EBI