Binding to Iron Quercetin Complexes Increases the Antioxidant Capacity of the Major Birch Pollen Allergen Bet v 1 and Reduces Its Allergenicity

Binding to Iron Quercetin Complexes Increases the Antioxidant Capacity of the Major Birch Pollen Allergen Bet v 1 and Reduces Its Allergenicity

Bet v 1 is the major allergen in birch pollen to which up to 95% of patients sensitized to birch respond. As a member of the pathogenesis-related PR 10 family, its natural function is implicated in plant defense, with a member of the PR10 family being reported to be upregulated under iron deficiency...

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Bibliographic Details
Main Authors: Andreas Regner, Nathalie Szepannek, Markus Wiederstein, Aila Fakhimahmadi, Luis F. Paciosis, Bart R. Blokhuis, Frank A. Redegeld, Gerlinde Hofstetter, Zdenek Dvorak, Erika Jensen-Jarolim, Karin Hufnagl, Franziska Roth-Walter
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Antioxidants
Subjects:
holo-Bet v 1
major allergen
immunomodulation
immune resilience
iron
quercetin
Online Access:https://www.mdpi.com/2076-3921/12/1/42

Internet

https://www.mdpi.com/2076-3921/12/1/42

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