Identification of endocrine-disrupting chemicals targeting key DCM-associated genes via bioinformatics and machine learning

Identification of endocrine-disrupting chemicals targeting key DCM-associated genes via bioinformatics and machine learning

Dilated cardiomyopathy (DCM) is a primary cause of heart failure (HF), with the incidence of HF increasing consistently in recent years. DCM pathogenesis involves a combination of inherited predisposition and environmental factors. Endocrine-disrupting chemicals (EDCs) are exogenous chemicals that i...

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Bibliographic Details
Main Authors: Shu Li, Shuice Liu, Xuefei Sun, Liying Hao, Qinghua Gao
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Dilated cardiomyopathy
Endocrine-disrupting chemicals
Bioinformatics analysis
Machine learning
EDCs-genes-disease Interactions
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324002434

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http://www.sciencedirect.com/science/article/pii/S0147651324002434

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