Autophagy Activation Protects Ocular Surface from Inflammation in a Dry Eye Model In Vitro

Autophagy Activation Protects Ocular Surface from Inflammation in a Dry Eye Model In Vitro

Inflammation is the main pathophysiology of dry eye, characterized by tear film instability and hyperosmolarity. The aim of this study was to investigate the association of inflammation and cellular autophagy using an in vitro dry eye model with primary cultured human corneal epithelial cells (HCECs...

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Bibliographic Details
Main Authors: Zhao Liu, Ding Chen, Xin Chen, Fang Bian, Ning Gao, Jinmiao Li, Stephen C. Pflugfelder, De-Quan Li
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
hyperosmolarity
autophagy
inflammation
human corneal epithelial cells
rapamycin
Online Access:https://www.mdpi.com/1422-0067/21/23/8966

Internet

https://www.mdpi.com/1422-0067/21/23/8966

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