Design, characterization and quantum chemical computations of a novel series of pyrazoles derivatives with potential anti-proinflammatory response

Design, characterization and quantum chemical computations of a novel series of pyrazoles derivatives with potential anti-proinflammatory response

The synthesis and characterization of the full family of 11 pyrazoles were performed by means of UV–Vis, FTIR, 1H NMR, 13C NMR, two-dimensional NMR experiments and DFT simulations. As pyrazoles are known for showing diverse biological actions, they were also tested in the NCI-60 cancer cell line pan...

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Bibliographic Details
Main Authors: Pia Burboa-Schettino, Carlos Bustos, Elies Molins, Xavier F. Figueroa, Jesus Llanquinao, Ximena Zarate, Gabriel Vallejos, Carlos Diaz-Uribe, William Vallejo, Eduardo Schott
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Arabian Journal of Chemistry
Subjects:
Anti-proinflammatory
Platelet-activating factor
Pyrazoles
NCI-60
DFT
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535220301969

Internet

http://www.sciencedirect.com/science/article/pii/S1878535220301969

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