Folate metabolism modifies chromosomal damage induced by 1,3-butadiene: results from a match-up study in China and in vitro experiments

Folate metabolism modifies chromosomal damage induced by 1,3-butadiene: results from a match-up study in China and in vitro experiments

Abstract Objectives To explore the role of folate metabolism in 1,3-Butadiene (BD)'s genotoxicity, we conducted a match-up study in BD-exposed workers in China to analyze the associations between the polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and the chromosomal damage induced...

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Bibliographic Details
Main Authors: Menglong Xiang, Zhi Wang, Peng Zou, Xi Ling, Guowei Zhang, Ziyuan Zhou, Jia Cao, Lin Ao
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Genes and Environment
Subjects:
1,3-butadiene
Folate metabolism
MTHFR
Polymorphism
Chromosomal damage
Online Access:https://doi.org/10.1186/s41021-021-00217-y

Internet

https://doi.org/10.1186/s41021-021-00217-y

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