OxLDL immune complexes activate complement and induce cytokine production by MonoMac 6 cells and human macrophages

OxLDL immune complexes activate complement and induce cytokine production by MonoMac 6 cells and human macrophages

Oxidized low density lipoprotein (OxLDL) is immunogenic and induces autoimmune responses in humans. OxLDL antibodies are predominantly of the proinflammatory IgG1 and IgG3 isotypes. We tested the capacity of immune complexes prepared with copper-oxidized human LDL and affinity chromatography-purifie...

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Bibliographic Details
Main Authors: Antonio F. Saad, Gabriel Virella, Charlyne Chassereau, Robert J. Boackle, Maria F. Lopes-Virella
Format: Article
Language:English
Published: Elsevier 2006-09-01
Series:Journal of Lipid Research
Subjects:
oxidized low density lipoprotein
autoimmunity
atherosclerosis
activated macrophages
inflammation
oxidized low density lipoprotein immune complexes
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520434649

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http://www.sciencedirect.com/science/article/pii/S0022227520434649

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