The effect of estrogenic compounds on psychosis-like behaviour in female rats.

17β-estradiol treatment has shown benefit against schizophrenia symptoms, however long-term use may be associated with negative side-effects. Selective estrogen receptor modulators, such as raloxifene and tamoxifen, have been proposed as suitable alternatives to 17β-estradiol. An isomer of 17β-estra...

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Bibliographic Details
Main Authors: Alyssa Sbisa, Maarten van den Buuse, Andrea Gogos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5868772?pdf=render