Drug mechanism enrichment analysis improves prioritization of therapeutics for repurposing

Abstract Background There is a pressing need for improved methods to identify effective therapeutics for diseases. Many computational approaches have been developed to repurpose existing drugs to meet this need. However, these tools often output long lists of candidate drugs that are difficult to in...

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Bibliographic Details
Main Authors: Belinda B. Garana, James H. Joly, Alireza Delfarah, Hyunjun Hong, Nicholas A. Graham
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-023-05343-8