Genetic Risk and Phenotype Correlation of Primary Open-Angle Glaucoma Based on Rho-Kinase Gene Polymorphisms

Genetic Risk and Phenotype Correlation of Primary Open-Angle Glaucoma Based on Rho-Kinase Gene Polymorphisms

Rho-associated coiled-coil kinase (ROCK) signaling can affect glaucoma risk by regulating trabecular meshwork outflow. We investigated the effect of <i>ROCK</i> gene polymorphism on the risks of primary open-angle glaucoma (POAG) and POAG-related phenotypes including intraocular pressure...

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Bibliographic Details
Main Authors: Yong-Woo Kim, Eunoo Bak, Seoyoung Wy, Seung-Chan Lee, Yu-Jeong Kim, Young-Kook Kim, Ki-Ho Park, Jin-Wook Jeoung
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Journal of Clinical Medicine
Subjects:
rho-associated coiled-coil kinase (ROCK)
single nucleotide polymorphism
primary open-angle glaucoma
Online Access:https://www.mdpi.com/2077-0383/10/9/1953

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https://www.mdpi.com/2077-0383/10/9/1953

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