The Balance between Hydrophobicity/Aromaticity and Positively Charged Residues May Influence the Cell Penetration Ability

The Balance between Hydrophobicity/Aromaticity and Positively Charged Residues May Influence the Cell Penetration Ability

Cell-penetrating peptides (CPPs) are commonly modified to increase their cellular uptake, alter the mechanism of penetration or enhance their endosomal release. Earlier, we described the internalization enhancement ability of the 4-((4-(dimethylamino)phenyl)azo)benzoyl (Dabcyl) group. We proved that...

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Bibliographic Details
Main Authors: Dóra Soltész, Ildikó Szabó, Zoltán Bánóczi
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Pharmaceutics
Subjects:
cell-penetrating peptide
oligoarginines
aromatic modification
Online Access:https://www.mdpi.com/1999-4923/15/4/1267

Internet

https://www.mdpi.com/1999-4923/15/4/1267

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