TRIC-A shapes oscillatory Ca2+ signals by interaction with STIM1/Orai1 complexes.

TRIC-A shapes oscillatory Ca2+ signals by interaction with STIM1/Orai1 complexes.

Trimeric intracellular cation (TRIC) channels have been proposed to modulate Ca2+ release from the endoplasmic reticulum (ER) and determine oscillatory Ca2+ signals. Here, we report that TRIC-A-mediated amplitude and frequency modulation of ryanodine receptor 2 (RyR2)-mediated Ca2+ oscillations and...

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Bibliographic Details
Main Authors: Niroj Shrestha, Bernadett Bacsa, Hwei Ling Ong, Susanne Scheruebel, Helmut Bischof, Roland Malli, Indu Suresh Ambudkar, Klaus Groschner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-04-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000700

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https://doi.org/10.1371/journal.pbio.3000700

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