Inhibition of RIP1-RIP3-mediated necroptosis attenuates renal fibrosis via Wnt3α/β-catenin/GSK-3β signaling in unilateral ureteral obstruction

Inhibition of RIP1-RIP3-mediated necroptosis attenuates renal fibrosis via Wnt3α/β-catenin/GSK-3β signaling in unilateral ureteral obstruction

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Renal fibrosis represents the final common outcome of chronic kidney disease of virtually any etiology. However, the mechanism underlying the evolution of renal fibrosis remains to be addressed. This study sought to clarify whether RIP1-RIP3-mediated necroptosis is involved in renal fibrosis via Wnt...

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Bibliographic Details
Main Authors: Shang Guo Piao, Jun Ding, Xue Jing Lin, Qi Yan Nan, Mei Ying Xuan, Yu Ji Jiang, Hai Lan Zheng, Ji Zhe Jin, Can Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555645/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555645/?tool=EBI

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