HuR-dependent SOD2 protein synthesis is an early adaptation to anchorage-independence

HuR-dependent SOD2 protein synthesis is an early adaptation to anchorage-independence

During metastasis cancer cells must adapt to survive loss of anchorage and evade anoikis. An important pro-survival adaptation is the ability of metastatic tumor cells to increase their antioxidant capacity and restore cellular redox balance. Although much is known about the transcriptional regulati...

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Bibliographic Details
Main Authors: Yeon Soo Kim, Priscilla W. Tang, Jaclyn E. Welles, Weihua Pan, Zaineb Javed, Amal Taher Elhaw, Karthikeyan Mythreye, Scot R. Kimball, Nadine Hempel
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S221323172200101X

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http://www.sciencedirect.com/science/article/pii/S221323172200101X

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