Fabrication and characterization of metformin-loaded PLGA/Collagen nanofibers for modulation of macrophage polarization for tissue engineering and regenerative medicine

Abstract In tissue engineering (TE) and regenerative medicine, the accessibility of engineered scaffolds that modulate inflammatory states is extremely necessary. The aim of the current work was to assess the efficacy of metformin (MET) incorporated in PLGA/Collagen nanofibers (Met-PLGA/Col NFs) to...

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Bibliographic Details
Main Authors: Akram Firouzi Amandi, Seyed Abbas Shahrtash, Shaylan Kalavi, Afshin Moliani, Hanieh Mousazadeh, Mehdi Rezai Seghin Sara, Mehdi Dadashpour
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Biotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12896-023-00825-2