Growth differentiation factor 15 (GDF15) elevation in children with newly diagnosed cancer

Growth differentiation factor 15 (GDF15) elevation in children with newly diagnosed cancer

BackgroundGrowth differentiation factor 15 (GDF15), an inflammatory marker and mediator of adult cancer cachexia, remains largely unexplored in children. GDF15 increases nausea, vomiting, and anorexia in cancer and contributes to malnutrition, with the potential to be a cachexia therapeutic target....

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Bibliographic Details
Main Authors: Daniel V. Runco, Linda A. DiMeglio, Charles P. Vanderpool, Yan Han, Joanne Daggy, Mary M. Kelley, Raya Mikesell, Teresa A. Zimmers
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Oncology
Subjects:
childhood cancer
pediatric
cachexia
GDF15
anthropometrics measurements
body composition
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1295228/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1295228/full

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