Growth differentiation factor 15 (GDF15) elevation in children with newly diagnosed cancer
BackgroundGrowth differentiation factor 15 (GDF15), an inflammatory marker and mediator of adult cancer cachexia, remains largely unexplored in children. GDF15 increases nausea, vomiting, and anorexia in cancer and contributes to malnutrition, with the potential to be a cachexia therapeutic target....
Main Authors: | Daniel V. Runco, Linda A. DiMeglio, Charles P. Vanderpool, Yan Han, Joanne Daggy, Mary M. Kelley, Raya Mikesell, Teresa A. Zimmers |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-12-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1295228/full |
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