Effect of TNF-α production inhibitors on the production of pro-inflammatory cytokines by peripheral blood mononuclear cells from HTLV-1-infected individuals

Human T lymphotropic virus type 1 (HTLV-1) is the causal agent of myelopathy/tropical spastic paraparesis (HAM/TSP), a disease mediated by the immune response. HTLV-1 induces a spontaneous proliferation and production of pro-inflammatory cytokines by T cells, and increasing interferon-γ (IFN-γ) and...

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Bibliographic Details
Main Authors: T. Luna, S.B. Santos, M. Nascimento, M.A.F. Porto, A.L. Muniz, E.M. Carvalho, A.R. Jesus
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2011-11-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011001100009&lng=en&tlng=en